What is the difference between betaine anhydrous and betaine hcl

Homocyst e ine, diet, and cardiovascular disease. A statement for healthcare professionals from the nutrition committee, American Heart Association. Efficacy and safety of oral betaine glucuronate in non-alcoholic steatohepatitis. A double-blind, randomized, parallel group, placebo-controlled prospective clinical study. Effect of folic acid and betaine supplementation on flow-mediated dilation: a randomized, controlled study in healthy volunteers.

PLoS Clin Trials. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans. PLoS Med. Low circulating folate and vitamin B6 concentrations.

Risk factors for stroke, peripheral vascular disease, and coronary artery disease. Aetiology and treatment of hyperhomocysteinaemia causing ischaemic stroke. Int J Clin Pract. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects.

Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia. Betaine-containing toothpaste relieves subjective symptoms of dry mouth. Acta Odontol Scand. Involvement of AMP-activated protein kinase in beneficial effects of betaine on high-sucrose diet-induced hepatic stenosis.

Inhibition of adiponectin production by homocysteine: a potential mechanism for alcoholic liver disease. Can lowering homocysteine levels reduce cardiovascular disease? N Engl J Med.

Homocysteine-lowering treatment: an overview. Expert Opin Pharmacother. Homocystinuria due to cystathione beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Associations between dietary intake of choline and betaine and lung cancer risk. PLoS One. Dietary choline and betaine intakes vary in an adult multiethnic population.

Zeisel SH. Betaine supplementation and blood lipids: fact or artifact? Nutr Rev. Choline and betaine intake is inversely associated with breast cancer risk: a two-stage case-control study in China. Cancer Sci. There is a distinct difference between betaine and betaine HCl. More importantly, betaine is a modified amino acid compound containing glycine with three methyl groups , while Betaine HCl is betaine hydrochloride which is a chemical compound that is produced in laboratories.

Overview and Key Difference 2. What is Betaine 3. What is Betaine HCl 4. Summary — Betaine vs Betaine HCl. Betaine is a modified amino acid compound containing glycine with three methyl groups. These methyl groups can serve as a methyl donor in several metabolic processes and is also useful in treating rare genetic causes of homocystinuria.

It is abbreviated as BET and is an amino acid that has potential benefits for fighting heart diseases, improvement of body composition, and helping the promotion of muscle gain and fat loss. Betaine can be identified as a neutral chemical compound having a positive charged cationic functional group e. Directions: As a dietary supplement, take mg up to two times daily, or as directed by a physician.

Accurate gram weight scale recommended. Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children. While both are taken as a nutritional supplement in treatment of high homocysteine levels, betaine hydrochloric acid is also sold as a digestive aid and as a supplemental source of hydrochloric acid for people who have a deficiency of stomach acid production; the anhydrous form does not include this benefit.

The HCl form also has an extremely sour taste while the anhydrous has a mild, pleasant taste. Betaine anhydrous, also called trimethylglycine, is an important nutrient derived from choline. Betaine carries and donates methyl molecules in the body to help make chemical processes work. Betaine anhydrous takes its name from the vegetable in which it was first discovered: sugar beets. It is also found in a variety of plant and animal sources.

The best dietary sources of betaine anhydrous include green leafy vegetables, cereal grains, seafood, legumes, wine and sugar beets. Studies have been conducted on whether TMG trimethylglycine may help reduce high levels of the amino acid homocysteine Wikipedia in the blood. Scientists are working to determine if a high homocysteine level has a direct negative effect on cardiovascular health or if it is simply a risk factor.

Betaine anhydrous also plays a role in the manufacture of carnitine and helps protect the kidneys.